“LORD, how are they increased that trouble me! Many are they that rise up against me.” Psalm 3:1 (KJV)
This Psalm is said to have been written by David while fleeing for his life from his son Absalom. Absalom had taken over the kingdom or at least part of it in anger, even hatred for his father.
What man, who loves his son or daughter, would not rather flee than to harm one of their children? Yet it grieved the heart of David, and he felt as though his world was coming after him.
If you will note, however; David went to God about the situation. That is the place we need to go when it seems the world is against us. When the world is against us, or even only one is against us let our destination be before the face of the LORD. Go now.